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Panoply™ Human AIRE Knockdown Stable Cell Line

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Cat.No.
CSC-DC000420
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
AIRE
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
AIRE
Synonyms
APS1; APSI; PGA1; AIRE1; APECED
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
O43918
Chromosome Location
21q22.3
Pathway
Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem; Ubiquitin mediated proteolysis, conserved biosystem;
Function
chromatin binding; histone binding; identical protein binding; protein binding; transcription regulatory region DNA binding; translation regulator activity; zinc ion binding;

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