Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR014862
| Cat. No. | CDFR014862 |
| Description | NativeORF clone of Rattus norvegicus agrin (Agrn) as transfection-ready DNA NM_175754.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Agrn |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | AGRN |
| Background | This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015] |
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