Human AGRN adenoviral particles

Name: Human AGRN adenoviral particles
SKU: AD00793Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD00793Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD00793Z
Description	Adenovirus with ORF of agrin (AGRN).
Gene	AGRN
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	AGRN agrin [ Homo sapiens ]
Gene Symbol	AGRN
GeneID	375790
Uni ProtID	O00468
mRNA Refseq	NM_198576.3
Protein Refseq	NP_940978.2
Chromosome Location	1p36.33
Function	laminin binding; protein binding; structural constituent of cytoskeleton;
Pathway	A tetrasaccharide linker sequence is required for GAG synthesis, organism-specific biosystem; Axon guidance, organism-specific biosystem; Chondroitin sulfate/dermatan sulfate metabolism, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Disease, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Glycosaminoglycan metabolism, organism-specific biosystem; HS-GAG biosynthesis, organism-specific biosystem; HS-GAG degradation, organism-specific biosystem; Heparan sulfate/heparin (HS-GAG) metabolism, organism-specific biosystem; MPS I - Hurler syndrome, organism-specific biosystem; MPS II - Hunter syndrome, organism-specific biosystem; MPS IIIA - Sanfilippo syndrome A, organism-specific biosystem; MPS IIIB - Sanfilippo syndrome B, organism-specific biosystem; MPS IIIC - Sanfilippo syndrome C, organism-specific biosystem; MPS IIID - Sanfilippo syndrome D, organism-specific biosystem; MPS IV - Morquio syndrome A, organism-specific biosystem; MPS IV - Morquio syndrome B, organism-specific biosystem; MPS IX - Natowicz syndrome, organism-specific biosystem; MPS VI - Maroteaux-Lamy syndrome, organism-specific biosystem; MPS VII - Sly syndrome, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem; Mucopolysaccharidoses, organism-specific biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem; NCAM1 interactions, organism-specific biosystem;
MIM	103320

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