Rat Actn1 cDNA Clone(NM_031005.3)

Name: Rat Actn1 cDNA Clone(NM_031005.3)
SKU: CDFR012481
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR012481

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Product Information

Gene Information

Cat. No.	CDFR012481
Description	NativeORF clone of Rattus norvegicus actinin, alpha 1 (Actn1) as transfection-ready DNA NM_031005.3
Product Type	cDAN Clone
Gene Abbr	Actn1
Species	Rat
Vector	pCMV6Entry

Target Gene

ACTN1

Background

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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