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shRNA set against Human ACTN1 (NM_001102.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH231030

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Gene Information

Cat. No. SHH231030
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ACTN1
Gene Name ACTN1 actinin, alpha 1 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name ACTN1 actinin, alpha 1 [ Homo sapiens ]
Gene Symbol ACTN1
Synonyms ACTN1; actinin, alpha 1; alpha-actinin-1; actinin 1 smooth muscle; non-muscle alpha-actinin-1; F-actin cross-linking protein; alpha-actinin cytoskeletal isoform; FLJ40884; FLJ54432;
GeneID 87
Uni ProtID P12814
mRNA Refseq BC003576
Chromosome Location 14q24.1
Function actin binding; actin filament binding; calcium ion binding; integrin binding; ion channel binding; protein binding; protein domain specific binding; vinculin binding;
Pathway Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cell junction organization, organism-specific biosystem;
MIM 102575
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