Rat Abcd1 ORF Clone(NM_001108821.1)

Name: Rat Abcd1 ORF Clone(NM_001108821.1)
SKU: CDCR375444
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR375444

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Product Information

Gene Information

Cat. No.	CDCR375444
Product Type	ORF Clone
Gene Abbr	Abcd1
Species	Rat
Tag	C-terminal Myc-DDK
ORF Size	2214 bp
Vector	pCMV6-Entry

Target Gene

ABCD1

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]

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