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Panoply™ Human ABCD1 Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC000060

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC000060
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene ABCD1
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 [ Homo sapiens ]
Gene Symbol ABCD1
Synonyms ALD; AMN; ALDP; ABC42
Gene ID 215
Uni Prot ID P33897
m RNA Refseq NM_000033.3
Protein Refseq NP_000024.2
Chromosome Location Xq28
Function ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; enzyme binding; identical protein binding; peroxisomal fatty-acyl-CoA transporter activity; peroxisomal fatty-acyl-CoA transporter activity; protein binding; protein homodimerization activity; transporter activity;
Pathway ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; ABCA transporters in lipid homeostasis, organism-specific biosystem; Beta-oxidation of very long chain fatty acids, organism-specific biosystem; Linoleic acid (LA) metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem;
MIM 300371
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