Rat Abcc1 cDNA Clone(NM_022281.2)

Name: Rat Abcc1 cDNA Clone(NM_022281.2)
SKU: CDFR011964
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR011964

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Product Information

Gene Information

Cat. No.	CDFR011964
Description	NativeORF clone of Rattus norvegicus ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1) as transfection-ready DNA NM_022281.2
Product Type	cDAN Clone
Gene Abbr	Abcc1
Species	Rat
Vector	pCMV6Entry

Target Gene

ABCC1

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]

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