Panoply™ Human ABCC1 Knockdown Stable Cell Line

Name: Panoply™ Human ABCC1 Knockdown Stable Cell Line
SKU: CSC-DC000049
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000049

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000049
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ABCC1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [ Homo sapiens ]
Gene Symbol	ABCC1
Synonyms	MRP; ABCC; GS-X; MRP1; ABC29
Gene Description	ATP-binding cassette, sub-family C (CFTR/MRP), member 1
GeneID	4363
Uni ProtID	P33527
mRNA Refseq	NM_004996.3
Protein Refseq	NP_004987.2
Chromosome Location	16p13.1
Function	ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; efflux transmembrane transporter activity; glutathione S-conjugate-exporting ATPase activity; glutathione transmembrane transporter activity; lipid-transporting ATPase activity; long-chain fatty acid transporter activity; sphingolipid transporter activity; transporter activity; xenobiotic-transporting ATPase activity;
Pathway	ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Arachidonic acid metabolism, organism-specific biosystem; Irinotecan Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem;
MIM	158343

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