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RRAS2 Validated sgRNA vector

For research use only. Not intended for any clinical use.

Cat. No. :   SKO0751

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Cat. No. SKO0751
Description Creative Biogene develops and optimizes genome editing technology to produce stable genome edited mammalian cell lines serving a wide-range of R&D activities in areas of basic research, diagnostic and therapeutic development. Our premade SuperKO sgRNA vectors are tailor-made to target many different genes respectively. We have successfully constructed a series of knockout cell lines using those sgRNAs.
Gene Abbr RRAS2
Reporter mCherry
Promoter U6
Resistance Amp
Selection Ampicillin
Vector Type Lentiviral Expression
Vector Length 7677 bp
Target Gene RRAS2
Background This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
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