Panoply™ Human TFAP2A Over-expressing Stable Cell Line

Name: Panoply™ Human TFAP2A Over-expressing Stable Cell Line
SKU: CSC-SC015832
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC015832

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC015832
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	TFAP2A
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) [ Homo sapiens ]
Gene Symbol	TFAP2A
Synonyms	AP-2; BOFS; AP2TF; TFAP2; AP-2alpha
Gene Description	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
GeneID	7020
Uni ProtID	P05549
mRNA Refseq	NM_001032280.2
Protein Refseq	NP_001027451.1
Chromosome Location	6p24
Function	RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; chromatin binding; core promoter proximal region sequence-specific DNA binding; protein binding; protein dimerization activity; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription coactivator activity; transcription regulatory region DNA binding; transcription regulatory region sequence-specific DNA binding;
Pathway	Caspase cascade in apoptosis, organism-specific biosystem; Neural Crest Differentiation, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem;
MIM	107580

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