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Panoply™ Human TFAP2A Knockdown Stable Cell Line

Cat.No.
CSC-DC015832
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
TFAP2A
Synonyms
AP-2; BOFS; AP2TF; TFAP2; AP-2alpha
Gene Description
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Gene ID
UniProt ID
P05549
mRNA Refseq
Protein Refseq
Chromosome Location
6p24
Function
RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; chromatin binding; core promoter proximal region sequence-specific DNA binding; protein binding; protein dimerization activity; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription coactivator activity; transcription regulatory region DNA binding; transcription regulatory region sequence-specific DNA binding;
Pathway
Caspase cascade in apoptosis, organism-specific biosystem; Neural Crest Differentiation, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem;
MIM

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