Panoply™ Human TAP2 Knockdown Stable Cell Line

Name: Panoply™ Human TAP2 Knockdown Stable Cell Line
SKU: CSC-DC015577
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC015577

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC015577
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TAP2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) [ Homo sapiens ]
Gene Symbol	TAP2
Synonyms	APT2; PSF2; ABC18; ABCB3; PSF-2; RING11; D6S217E
Gene Description	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Gene ID	6891
Uni Prot ID	Q03519
m RNA Refseq	NM_000544.3
Protein Refseq	NP_000535.3
Chromosome Location	6p21.3
Function	ATP binding; MHC class I protein binding; TAP1 binding; TAP1 binding; TAP2 binding; oligopeptide-transporting ATPase activity; peptide antigen binding; peptide antigen-transporting ATPase activity; contributes_to peptide transporter activity; protein binding; tapasin binding; transporter activity;
Pathway	ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem;
MIM	170261

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