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TAP2


Official Full Name
transporter 2, ATP binding cassette subfamily B member
Organism
Homo sapiens
Gene ID
6891
Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]
Synonyms
APT2; PSF2; ABC18; ABCB3; PSF-2; MHC1D2; RING11; D6S217E

Cat.No. Product Name Price
SHH423028 shRNA set against Mouse TAP2 (NM_011530.3) Inquiry
SHH423032 shRNA set against Rat TAP2 (NM_032056.3) Inquiry
SHL056053 shRNA set against Human TAP2(NM_000544.3) Inquiry
SHL056070 shRNA set against Rat Tap2(NM_032056.2) Inquiry
SHL056107 shRNA set against Human TAP2(NM_018833.2) Inquiry
SHW002664 shRNA set against Chicken TAP2 (NM_001099357) Inquiry
Cat.No. Product Name Price
CDCR380008 Rat Tap2 ORF Clone(NM_032056.3) Inquiry
CDFG002040 Human TAP2 cDNA Clone(NM_018833.2) Inquiry
CDFH019205 Human TAP2 cDNA Clone(NM_000544.3) Inquiry
CDFR012994 Rat Tap2 cDNA Clone(NM_032056.3) Inquiry
MiUTR1H-10176 TAP2 miRNA 3'UTR clone Inquiry
MiUTR1H-10177 TAP2 miRNA 3'UTR clone Inquiry
CDCB164139 Chicken TAP2 ORF Clone (NM_001099357) Inquiry
CDCB186867 Rabbit TAP2 ORF clone (XM_008262761.1) Inquiry
CDCH088772 human TAP2 ORF clone (NM_018833.2) Inquiry
CDCH088774 human TAP2 ORF clone (NM_000544.3) Inquiry
CDCR250529 Mouse Tap2 ORF Clone(NM_011530.3) Inquiry
CDCS405733 Human TAP2 ORF Clone (BC002751) Inquiry
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