Panoply™ Human SLC11A2 Over-expressing Stable Cell Line

Name: Panoply™ Human SLC11A2 Over-expressing Stable Cell Line
SKU: CSC-SC014313
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC014313

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC014313
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	SLC11A2
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 [ Homo sapiens ]
Gene Symbol	SLC11A2
Synonyms	DCT1; DMT1; NRAMP2
GeneID	4891
Uni ProtID	P49281
mRNA Refseq	NM_000617.2
Protein Refseq	NP_000608.1
Chromosome Location	12q13
Function	cadmium ion binding; cadmium ion transmembrane transporter activity; NOT calcium ion transmembrane transporter activity; NOT chromium ion transmembrane transporter activity; cobalt ion binding; cobalt ion transmembrane transporter activity; cobalt ion transmembrane transporter activity; copper ion binding; copper ion transmembrane transporter activity; ferrous iron transmembrane transporter activity; hydrogen ion transmembrane transporter activity; inorganic cation transmembrane transporter activity; iron ion binding; lead ion transmembrane transporter activity; manganese ion binding; manganese ion transmembrane transporter activity; nickel cation binding; nickel cation transmembrane transporter activity; nickel cation transmembrane transporter activity; protein binding; solute:hydrogen symporter activity; vanadium ion transmembrane transporter activity; zinc ion binding; zinc ion transmembrane transporter activity; NOT zinc ion transmembrane transporter activity;
Pathway	HIF-2-alpha transcription factor network, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metal ion SLC transporters, organism-specific biosystem; Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem;
MIM	600523

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