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Panoply™ Human SKP2 Knockdown Stable Cell Line

Cat.No.
CSC-DC014294
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
SKP2
Synonyms
p45; FBL1; FLB1; FBXL1
Gene Description
S-phase kinase-associated protein 2 (p45)
Gene ID
UniProt ID
B4DJT4
mRNA Refseq
Protein Refseq
Chromosome Location
5p13
Function
identical protein binding; protein binding; ubiquitin-protein ligase activity;
Pathway
APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; C-MYC pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem;
MIM

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