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RAPGEF3

Official Full Name
Rap guanine nucleotide exchange factor 3
Organism
Homo sapiens
GeneID
10411
Background
Enables guanyl-nucleotide exchange factor activity and protein domain specific binding activity. Involved in several processes, including Rap protein signal transduction; cellular response to cAMP; and regulation of syncytium formation by plasma membrane fusion. Located in several cellular components, including filopodium; lamellipodium; and microvillus. Implicated in nicotine dependence. Biomarker of congestive heart failure. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
EPAC; EPAC1; bcm910; HSU79275; CAMP-GEFI;

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