Panoply™ Human PRKG1 Knockdown Stable Cell Line

Name: Panoply™ Human PRKG1 Knockdown Stable Cell Line
SKU: CSC-DC012411
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC012411

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC012411
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	PRKG1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PRKG1 protein kinase, cGMP-dependent, type I [ Homo sapiens ]
Gene Symbol	PRKG1
Synonyms	PRKG1; protein kinase, cGMP-dependent, type I; PRKG1B, PRKGR1B; cGMP-dependent protein kinase 1; PGK; PKG; protein kinase, cGMP-dependent, regulatory, type I, beta; 1; cGK; cGK1; cGKI; cGK 1; PRKG1B; PRKGR1B; cGKI-BETA; cGKI-alpha; FLJ36117; MGC71944; DKFZp686K042;
Gene ID	5592
Uni Prot ID	Q13976
m RNA Refseq	BC127090
Chromosome Location	10q11.2
Function	ATP binding; cGMP binding; cGMP-dependent protein kinase activity; calcium channel regulator activity; nucleotide binding; protein binding; protein serine/threonine kinase activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Gap junction, organism-specific biosystem; Gap junction, conserved biosystem; Hemostasis, organism-specific biosystem; Immune System, organism-specific biosystem; Long-term depression, organism-specific biosystem; Long-term depression, conserved biosystem;
MIM	176894

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