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Panoply™ Human PLA2G1B Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC011864

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC011864
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene PLA2G1B
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name PLA2G1B phospholipase A2, group IB (pancreas) [ Homo sapiens ]
Gene Symbol PLA2G1B
Synonyms PLA2; PLA2A; PPLA2
Gene Description phospholipase A2, group IB (pancreas)
GeneID 5319
Uni ProtID P04054
mRNA Refseq NM_000928.2
Protein Refseq NP_000919.1
Chromosome Location 12q23-q24.1
Function bile acid binding; calcium ion binding; calcium-dependent phospholipase A2 activity; cell surface binding; phospholipase A2 activity; receptor binding; receptor binding;
Pathway Acyl chain remodelling of PC, organism-specific biosystem; Acyl chain remodelling of PE, organism-specific biosystem; Acyl chain remodelling of PG, organism-specific biosystem; Acyl chain remodelling of PI, organism-specific biosystem; Acyl chain remodelling of PS, organism-specific biosystem; Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem;
MIM 172410
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