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Panoply™ Human ORC1 Knockdown Stable Cell Line

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Cat.No.
CSC-DC011123
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
ORC1
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
ORC1
Synonyms
ORC1L; PARC1; HSORC1
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q13415
Chromosome Location
1p32
Pathway
Activation of ATR in response to replication stress, organism-specific biosystem; Activation of the pre-replicative complex, organism-specific biosystem; Assembly of the ORC complex at the origin of replication, organism-specific biosystem; Assembly of the pre-replicative complex, organism-specific biosystem; Association of licensing factors with the pre-replicative complex, organism-specific biosystem; CDC6 association with the ORC:origin complex, organism-specific biosystem; CDT1 association with the CDC6:ORC:origin complex, organism-specific biosystem;
Function
ATP binding; DNA binding; nucleoside-triphosphatase activity; protein binding;

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