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Panoply™ Human LEF1 Knockdown Stable Cell Line

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Cat.No.
CSC-DC008628
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
LEF1
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
LEF1
Synonyms
LEF-1; TCF10; TCF7L3; TCF1ALPHA
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q659G9
Chromosome Location
4q23-q25
Pathway
Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem;
Function
C2H2 zinc finger domain binding; DNA binding; DNA binding, bending; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; armadillo repeat domain binding; beta-catenin binding; beta-catenin binding; chromatin binding; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; enhancer binding; estrogen receptor activity; estrogen receptor binding; gamma-catenin binding; histone binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding;

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