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JAM3


Official Full Name
junctional adhesion molecule 3
Organism
Homo sapiens
Gene ID
83700
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
Synonyms
JAMC; JAM-2; JAM-3; JAM-C

Cat.No. Product Name Price
SHH321995 shRNA set against Human JAM3 (NM_032801.4) Inquiry
SHH321999 shRNA set against Mouse JAM3 (NM_023277.4) Inquiry
SHH322003 shRNA set against Rat JAM3 (NM_001004269.1) Inquiry
SHL185590 shRNA set against Rat Jam3(NM_001004269.1) Inquiry
Cat.No. Product Name Price
CDCR368337 Rat Jam3 ORF Clone(NM_001004269.1) Inquiry
CDFR001416 Rat Jam3 cDNA Clone(NM_001004269.1) Inquiry
MiUTR1R-02732 JAM3 miRNA 3'UTR clone Inquiry
MiUTR4H-TG04627 JAM3 miRNA 3'UTR clone Inquiry
CDCB157288 Mouse JAM3 ORF clone (NM_023277.3) Inquiry
CDCB160238 Human JAM3 ORF clone (NM_032801.3) Inquiry
CDCB189920 Rabbit JAM3 ORF clone (XM_008248363.1) Inquiry
CDCH387494 Human JAM3 ORF clone(NM_032801.4) Inquiry
CDCH387495 Mouse JAM3 ORF clone(NM_023277.4) Inquiry
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