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Panoply™ Human HMGCR Knockdown Stable Cell Line

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Cat.No.
CSC-DC007122
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
HMGCR
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
HMGCR
Synonyms
LDLCQ3
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
P04035
Chromosome Location
5q13.3-q14
Pathway
AMPK signaling, organism-specific biosystem; Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, organism-specific biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, conserved biosystem; Cholesterol Biosynthesis, organism-specific biosystem;
Function
NADPH binding; coenzyme binding; hydroxymethylglutaryl-CoA reductase (NADPH) activity; hydroxymethylglutaryl-CoA reductase activity; protein homodimerization activity;

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