Panoply™ Human HDAC7 Over-expressing Stable Cell Line

Name: Panoply™ Human HDAC7 Over-expressing Stable Cell Line
SKU: CSC-SC006892
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC006892

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC006892
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	HDAC7
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	HDAC7 histone deacetylase 7 [ Homo sapiens ]
Gene Symbol	HDAC7A
Synonyms	HD7A; HDAC7A
Gene Description	histone deacetylase 7A
GeneID	798603
Uni ProtID	Q8WUI4
mRNA Refseq	NM_001098416.2
Protein Refseq	NP_001091886.1
Chromosome Location	12q13.1
Function	14-3-3 protein binding; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); activating transcription factor binding; chromatin binding; metal ion binding; protein kinase C binding; protein kinase binding; repressing transcription factor binding; transcription corepressor activity;
Pathway	Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Cell cycle, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem;
MIM	606542

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