Human HDAC9 adenoviral particles

Name: Human HDAC9 adenoviral particles
SKU: AD07388Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD07388Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD07388Z
Description	Adenovirus with ORF of histone deacetylase 9 (HDAC9), transcript variant 9.
Gene	HDAC9
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	HDAC9 histone deacetylase 9 [ Homo sapiens ]
Gene Symbol	HDAC9
Synonyms	HD7; HD9; HD7b; HDAC; HDRP; MITR; HDAC7; HDAC7B; HDAC9B; HDAC9FL
Gene Description	histone deacetylase 9
GeneID	9734
Uni ProtID	B7Z928
mRNA Refseq	NM_001204147.1
Protein Refseq	NP_001191076.1
Chromosome Location	7p21.1
Function	NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K18 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity; NOT histone deacetylase activity; histone deacetylase binding; histone deacetylase binding; metal ion binding; protein binding; protein deacetylase activity; protein kinase C binding; repressing transcription factor binding; repressing transcription factor binding; repressing transcription factor binding; transcription corepressor activity; transcription factor binding; transcription factor binding;
Pathway	Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Neural Crest Differentiation, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
MIM	606543

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