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Panoply™ Human GLI3 Knockdown Stable Cell Line

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Cat.No.
CSC-DC006316
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
GLI3
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Gene Name
GLI3 GLI family zinc finger 3 [ Homo sapiens ]
Official Symbol
GLI3
Synonyms
PHS; ACLS; GCPS; PAPA; PAPB; PAP-A; PAPA1; PPDIV; GLI3FL; GLI3-190
GeneID
2737
mRNA Refseq
NM_000168.5
Protein Refseq
NP_000159.3
MIM
165240
UniProt ID
P10071
Chromosome Location
7p13
Pathway
Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Endochondral Ossification, organism-specific biosystem; Hedgehog Signaling Pathway, organism-specific biosystem; Hedgehog signaling events mediated by Gli proteins, organism-specific biosystem; Hedgehog signaling pathway, organism-specific biosystem; Hedgehog signaling pathway, conserved biosystem;
Function
beta-catenin binding; chromatin binding; histone acetyltransferase binding; histone deacetylase binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding;

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