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Panoply™ Human ELANE Knockdown Stable Cell Line

Cat.No.
CSC-DC004848
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ELA2
Synonyms
GE; NE; HLE; HNE; ELA2; SCN1; PMN-E
Gene Description
elastase 2, neutrophil
Gene ID
UniProt ID
P08246
mRNA Refseq
Protein Refseq
Chromosome Location
19p13.3
Function
bacterial cell surface binding; cytokine binding; endopeptidase activity; heparin binding; peptidase activity; protease binding; protein binding; serine-type endopeptidase activity;
Pathway
Activation of Matrix Metalloproteinases, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Systemic lupus erythematosus, organism-specific biosystem; Systemic lupus erythematosus, conserved biosystem; Transcriptional misregulation in cancer, organism-specific biosystem;
MIM

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