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DLC1

Official Full Name
DLC1 Rho GTPase activating protein
Organism
Homo sapiens
GeneID
10395
Background
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]
Synonyms
HP; ARHGAP7; STARD12; p122-RhoGAP;

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