Panoply™ Human CYP7A1 Knockdown Stable Cell Line

Name: Panoply™ Human CYP7A1 Knockdown Stable Cell Line
SKU: CSC-DC003988
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC003988

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC003988
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	CYP7A1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 [ Homo sapiens ]
Gene Symbol	CYP7A1
Synonyms	CP7A; CYP7; CYPVII
Gene Description	cytochrome P450, family 7, subfamily A, polypeptide 1
Gene ID	1581
Uni Prot ID	P22680
m RNA Refseq	NM_000780.3
Protein Refseq	NP_000771.2
Chromosome Location	8q11-q12
Function	cholesterol 7-alpha-monooxygenase activity; electron carrier activity; heme binding; iron ion binding;
Pathway	Bile acid and bile salt metabolism, organism-specific biosystem; Bile acid biosynthesis, cholesterol => cholate, organism-specific biosystem; Bile acid biosynthesis, cholesterol => cholate, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem;
MIM	118455

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