Panoply™ Human CASP8 Over-expressing Stable Cell Line

Name: Panoply™ Human CASP8 Over-expressing Stable Cell Line
SKU: CSC-SC002399
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC002399

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC002399
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	CASP8
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CASP8 caspase 8, apoptosis-related cysteine peptidase [ Homo sapiens ]
Gene Symbol	CASP8
Synonyms	CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8
Gene Description	caspase 8, apoptosis-related cysteine peptidase
Gene ID	841
Uni Prot ID	Q14790
m RNA Refseq	NM_001080124.1
Protein Refseq	NP_001073593.1
Chromosome Location	2q33-q34
Function	cysteine-type endopeptidase activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; identical protein binding; protein binding; tumor necrosis factor receptor binding;
Pathway	Activation of Pro-Caspase 8, organism-specific biosystem; Activation, myristolyation of BID and translocation to mitochondria, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem;
MIM	601763

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