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Panoply™ Human CASP8 Knockdown Stable Cell Line

Cat.No.
CSC-DC002399
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
CASP8
Synonyms
CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8
Gene Description
caspase 8, apoptosis-related cysteine peptidase
Gene ID
UniProt ID
Q14790
mRNA Refseq
Protein Refseq
Chromosome Location
2q33-q34
Function
cysteine-type endopeptidase activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; identical protein binding; protein binding; tumor necrosis factor receptor binding;
Pathway
Activation of Pro-Caspase 8, organism-specific biosystem; Activation, myristolyation of BID and translocation to mitochondria, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem;
MIM

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