Panoply™ Human AXIN1 Knockdown Stable Cell Line

Name: Panoply™ Human AXIN1 Knockdown Stable Cell Line
SKU: CSC-DC001247
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC001247

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC001247
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	AXIN1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	AXIN1 axin 1 [ Homo sapiens ]
Gene Symbol	AXIN1
Synonyms	AXIN1; axin 1; axin-1; PPP1R49; protein phosphatase 1; regulatory subunit 49; axis inhibitor 1; fused, mouse, homolog of; axis inhibition protein 1; protein phosphatase 1, regulatory subunit 49; AXIN; MGC52315;
GeneID	8312
Uni ProtID	O15169
mRNA Refseq	BC044648
Chromosome Location	16p13.3
Function	GTPase activator activity; I-SMAD binding; R-SMAD binding; SMAD binding; armadillo repeat domain binding; armadillo repeat domain binding; beta-catenin binding; beta-catenin binding; enzyme binding; identical protein binding; p53 binding; protein C-terminus binding; protein binding; protein complex scaffold; protein complex scaffold; protein homodimerization activity; protein kinase binding; pr
Pathway	Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Beta-catenin phosphorylation cascade, organism-specific biosystem; C-MYC pathway, organism-specific biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Colorectal cancer, organism-specific biosystem; Colorectal cancer, conserved biosystem;
MIM	603816

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