Panoply™ Human ARNTL Over-expressing Stable Cell Line

Name: Panoply™ Human ARNTL Over-expressing Stable Cell Line
SKU: CSC-SC000965
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC000965

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC000965
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	ARNTL
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ARNTL aryl hydrocarbon receptor nuclear translocator-like [ Homo sapiens ]
Gene Symbol	ARNTL
Synonyms	TIC; JAP3; MOP3; BMAL1; PASD3; BMAL1c; bHLHe5
Gene Description	aryl hydrocarbon receptor nuclear translocator-like
Gene ID	406
Uni Prot ID	O00327
m RNA Refseq	NM_001030273.1
Protein Refseq	NP_001025444.1
Chromosome Location	11p15
Function	DNA binding; Hsp90 protein binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; aryl hydrocarbon receptor binding; bHLH transcription factor binding; protein heterodimerization activity; signal transducer activity;
Pathway	BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian Repression of Expression by REV-ERBA, organism-specific biosystem; Circadian rhythm - mammal, organism-specific biosystem; Circadian rhythm - mammal, conserved biosystem; Circadian rhythm pathway, organism-specific biosystem; Diurnally regulated genes with circadian orthologs, organism-specific biosystem;
MIM	602550

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