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Panoply™ Human ARNTL Knockdown Stable Cell Line

Cat.No.
CSC-DC000965
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ARNTL
Synonyms
TIC; JAP3; MOP3; BMAL1; PASD3; BMAL1c; bHLHe5
Gene Description
aryl hydrocarbon receptor nuclear translocator-like
Gene ID
UniProt ID
O00327
mRNA Refseq
Protein Refseq
Chromosome Location
11p15
Function
DNA binding; Hsp90 protein binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; aryl hydrocarbon receptor binding; bHLH transcription factor binding; protein heterodimerization activity; signal transducer activity;
Pathway
BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian Repression of Expression by REV-ERBA, organism-specific biosystem; Circadian rhythm - mammal, organism-specific biosystem; Circadian rhythm - mammal, conserved biosystem; Circadian rhythm pathway, organism-specific biosystem; Diurnally regulated genes with circadian orthologs, organism-specific biosystem;
MIM

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