Panoply™ Human ACVRL1 Over-expressing Stable Cell Line

Name: Panoply™ Human ACVRL1 Over-expressing Stable Cell Line
SKU: CSC-SC000219
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC000219

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC000219
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	ACVRL1
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ACVRL1 activin A receptor type II-like 1 [ Homo sapiens ]
Gene Symbol	ACVRL1
Synonyms	HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
Gene Description	activin A receptor type II-like 1
Gene ID	94
Uni Prot ID	P37023
m RNA Refseq	NM_000020.2
Protein Refseq	NP_000011.2
Chromosome Location	12q13.13
Function	ATP binding; SMAD binding; activin binding; activin receptor activity, type I; contributes_to activin receptor activity, type I; metal ion binding; protein binding; protein kinase binding; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta binding; contributes_to transforming growth factor beta receptor activity, type I; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity;
Pathway	ALK1 pathway, organism-specific biosystem; ALK1 signaling events, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem;
MIM	601284

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