Human ACVRL1(His) HEK293 Cell Lysate

Name: Human ACVRL1(His) HEK293 Cell Lysate
SKU: CLOE-1760
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1760 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1760
Introduction	This cell lysate over-expresses the extracellular domain of human ACVRL1 (NP_000011.2) (Met 1-Gln 118) fused with a polyhistidine tag at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	ACVRL1
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	ACVRL1 activin A receptor type II-like 1 [ Homo sapiens ]
Gene Symbol	ACVRL1
Synonyms	HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
Gene Description	activin A receptor type II-like 1
Gene ID	94
Uni Prot ID	P37023
m RNA Refseq	NM_000020.2
Protein Refseq	NP_000011.2
Chromosome Location	12q13.13
Function	ATP binding; SMAD binding; activin binding; activin receptor activity, type I; contributes_to activin receptor activity, type I; metal ion binding; protein binding; protein kinase binding; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta binding; contributes_to transforming growth factor beta receptor activity, type I; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity;
Pathway	ALK1 pathway, organism-specific biosystem; ALK1 signaling events, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem;
MIM	601284

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