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Nos2 Knockout Mouse Bone Marrow Macrophages

Cat.No.
CSC-RK0146
Abbr
MPBMMACs-Nos2 Knockout
Alias
NOS2,MAC-NOS,iNOS,Nos-2,Nos2a,i-NOS,NOS-II
Growth Properties
Adherent
Host Cell
Bone marrow macrophages
Shipping
Dry ice
Species
Mouse
Background
Nitric oxide synthase, inducible (iNOS) is an enzyme that in humans is encoded by the NOS2 gene. Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

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