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Mouse Rtel1 cDNA Clone(NM_001001882.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG016732

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Gene Information

Cat. No. CDFG016732
Product Type cDNA clone
Gene Abbr Rtel1
Species Mouse
ORF Size 3630bp
Size 10 ug
Vector pCMV6Entry
Target Gene RTEL1
Background This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
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