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Mouse Rtel1 ORF Clone(NM_001166667.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR241268

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Product Information

Gene Information

Cat. No. CDCR241268
Product Type ORF Clone
Gene Abbr Rtel1
Species Mouse
Tag C-terminal TurboGFP
ORF Size 3495 bp
Size 10 ug
Vector pCMV6-AC-GFP
Target Gene RTEL1
Background This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
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