Mouse Ptprc ORF Clone(NM_011210.4)

Name: Mouse Ptprc ORF Clone(NM_011210.4)
SKU: CDCR250289
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR250289

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Product Information

Gene Information

Cat. No.	CDCR250289
Product Type	ORF Clone
Gene Abbr	Ptprc
Species	Mouse
Tag	C-terminal TurboGFP
ORF Size	3459 bp
Size	10 ug
Vector	pCMV6-AC-GFP

Target Gene

PTPRC

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

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