Mouse Ptprc Insect Cell Lysate

Name: Mouse Ptprc Insect Cell Lysate
SKU: CLOE-2506
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-2506 Host Cell : Baculovirus-Insect cell

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-2506
Introduction	This cell lysate over-expresses mouse Ptprc (Arg453-Ser1152) fused with C-terminal amino acids (DDDDK). Purification of target protein (s) from this cell lysate has been verified.
Target Gene	Ptprc
Host Cell	Baculovirus-Insect cell
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Target Gene

PTPRC

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

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