Mouse Prom1 ORF clone (NM_001163578.1)

Name: Mouse Prom1 ORF clone (NM_001163578.1)
SKU: CDCH068192
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH068192

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Product Information

Gene Information

Cat. No.	CDCH068192
Description	Mus musculus prominin 1 (Prom1), transcript variant 3, mRNA.
Product Type	ORF clone
Gene Abbr	Prom1
Species	Mouse
ORF Size	2505bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

PROM1

Background

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

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