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Mouse Lass3 cDNA Clone(NM_001164201.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG020587

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Gene Information

Cat. No. CDFG020587
Product Type cDNA clone
Gene Abbr Lass3
Species Mouse
ORF Size 1260bp
Size 10 ug
Vector pCMV6Entry
Target Gene CERS3
Background This gene is a member of the ceramide synthase family of genes. The ceramide synthase enzymes regulate sphingolipid synthesis by catalyzing the formation of ceramides from sphingoid base and acyl-coA substrates. This family member is involved in the synthesis of ceramides with ultra-long-chain acyl moieties (ULC-Cers), important to the epidermis in its role in creating a protective barrier from the environment. The protein encoded by this gene has also been implicated in modification of the lipid structures required for spermatogenesis. Mutations in this gene have been associated with male fertility defects, and epidermal defects, including ichthyosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
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