Rat Cers3 cDNA Clone(NM_001127561.1)

Name: Rat Cers3 cDNA Clone(NM_001127561.1)
SKU: CDFR009587
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR009587

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Product Information

Gene Information

Cat. No.	CDFR009587
Description	NativeORF clone of Rattus norvegicus LAG1 homolog, ceramide synthase 3 (Lass3) as transfection-ready DNA NM_001127561.1
Product Type	cDAN Clone
Gene Abbr	Cers3
Species	Rat
Vector	pCMV6Entry

Target Gene

CERS3

Background

This gene is a member of the ceramide synthase family of genes. The ceramide synthase enzymes regulate sphingolipid synthesis by catalyzing the formation of ceramides from sphingoid base and acyl-coA substrates. This family member is involved in the synthesis of ceramides with ultra-long-chain acyl moieties (ULC-Cers), important to the epidermis in its role in creating a protective barrier from the environment. The protein encoded by this gene has also been implicated in modification of the lipid structures required for spermatogenesis. Mutations in this gene have been associated with male fertility defects, and epidermal defects, including ichthyosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]

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