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Mouse Kctd1 cDNA Clone(NM_001142731.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG019244

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Gene Information

Cat. No. CDFG019244
Product Type cDNA clone
Gene Abbr Kctd1
Species Mouse
ORF Size 2586bp
Size 10 ug
Vector pCMV6Entry
Target Gene KCTD1
Background This gene encodes a protein containing a BTB (Broad-complex, tramtrack and bric a brac), also known as a POZ (POxvirus and zinc finger) protein-protein interaction domain. The encoded protein negatively regulates the AP-2 family of transcription factors and the Wnt signaling pathway. A mechanism for the modulation of Wnt signaling has been proposed in which the encoded protein enhances ubiquitination and degradation of the beta-catenin protein. Mutations in this gene have been identified in Scalp-ear-nipple (SEN) syndrome. [provided by RefSeq, May 2017]
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