Mouse HGF ORF clone(NM_010427.4)

Name: Mouse HGF ORF clone(NM_010427.4)
SKU: CDCL184569
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL184569

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Product Information

Gene Information

Cat. No.	CDCL184569
Description	ORF Clone of Mus musculus hepatocyte growth factor DNA.
Product Type	ORF clone
Gene Abbr	HGF
Species	Mouse
ORF Size	2187bp
Vector	pMD18-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

HGF

Background

This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq, Nov 2015]

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