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Mouse Grm5 ORF clone (NM_001081414.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL114879

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Product Information

Gene Information

Cat. No. CDCL114879
Description Mus musculus glutamate receptor, metabotropic 5 (Grm5), transcript variant a, mRNA.
Product Type ORF clone
Gene Abbr Grm5
Species Mouse
ORF Size 3516bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene Grm5
Background Enables protein tyrosine kinase activator activity. Involved in several processes, including cellular response to amyloid-beta; learning or memory; and positive regulation of calcium-mediated signaling. Acts upstream of or within learning; locomotory behavior; and regulation of long-term neuronal synaptic plasticity. Located in cytoplasm; neuron projection; and plasma membrane. Is active in Schaffer collateral - CA1 synapse and dendrite. Is expressed in central nervous system and retina. Used to study schizophrenia. Orthologous to human GRM5 (glutamate metabotropic receptor 5). [provided by Alliance of Genome Resources, Feb 2025]
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