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Mouse Ephb4 cDNA Clone(NM_001159571.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG019903

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Gene Information

Cat. No. CDFG019903
Product Type cDNA clone
Gene Abbr Ephb4
Species Mouse
ORF Size 2991bp
Size 10 ug
Vector pCMV6Entry
Target Gene EPHB4
Background Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008]
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