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Mouse Ddc cDNA Clone(NM_001190448.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG021454

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Gene Information

Cat. No. CDFG021454
Product Type cDNA clone
Gene Abbr Ddc
Species Mouse
ORF Size 1443bp
Size 10 ug
Vector pCMV6Entry
Target Gene DDC
Background The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
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