Mouse Ddc Insect Cell Lysate

Name: Mouse Ddc Insect Cell Lysate
SKU: CLOE-2453
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-2453 Host Cell : Baculovirus-Insect cell

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-2453
Introduction	This cell lysate over-expresses mouse Ddc (O88533) (Met 1-Glu 480) fused with C-terminal his tag. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	Ddc
Host Cell	Baculovirus-Insect cell
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Target Gene

DDC

Background

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]

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